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Confounding Complexity of Machine Action
Henrik Sætra
Jan 01, 2021
In this article, the core concepts in Thomas Hobbes's framework of representation and responsibility are applied to the question of machine responsibility and the responsibility gap and the retribution gap. The method is...
Published by: IGI Global
Speculative Geology
Dale E. Snow
Dec 20, 2020
We are not at peace with nature now. Whether it is the record-setting rain on the east coast or the raging wildfires in the west, distant news of melting permafrost or bleaching coral reefs, or the unexpected eruption of Mount...
Published by: Memorial University Libraries
APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
João Pedro Ferrari-Souza, Firoza Z Lussier, Douglas T Leffa, Joseph Therriault, Cécile Tissot, Bruna Bellaver, Pâmela CL Ferreira, Maura Malpetti, Yi-Ting Wang, Guilherme Povala, Andréa L Benedet, Nicholas J Ashton, Mira Chamoun, Stijn Servaes, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, John T O'Brien, James B Rowe, Ann D Cohen, Oscar L Lopez, Dana L Tudorascu, Thomas K Karikari, William E Klunk, Victor L Villemagne, Jean-Paul Soucy, Serge Gauthier, Diogo O Souza, Henrik Zetterberg, Kaj Blennow, Eduardo R Zimmer, Pedro Rosa-Neto, Tharick A Pascoal
Apr 17, 2023
Animal studies suggest that the apolipoprotein E ε4 (APOEε4) allele is a culprit of early microglial activation in Alzheimer's disease (AD). Here, we tested the association between APOEε4 status and microglial activation in...